OpenPGP 1.0 cards should work fine with OpenSC.
However right now the openpgp card can only be modified with gnupg. So you need to use gnupg to use it / create keys / store keys etc.
In theory opensc has an emulation that can be used so we can use those keys on the card, too, but in practice I haven't heard of anyone using it successfully for a long time. If you find time to test, please report back, both success or failure, so we can have a look.
Also I'm not sure how good the other applications will work with that card. nearly every app (except gnupg) expects some x.509 certificate on the card and I have no idea if those can be created and/or stored with gnupg on the card. But I think they can - at linuxtag I saw diagrams at the bsi booth that indicate gnupg can do both pgp and smime so I guess it can handle it.
Latest information indicates the card cannot store X.509 certificates. Thus most applications will not be able to use it. Also remember the card is limited to a maximum of three RSA keys, and the keys are limited to 1024 bit size.